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HaystackAnalytics with its infexn NGS diagnostic test has successfully diagnosed a rare infection, known as Murine Typhus caused by an intracellular bacteria or Rickettsia typhi transmitted by fleas. This was made possible within 20 hours of sample collection. This result was later validated by Christian Medical College (CMC), Vellore.
In its communication, the company said infections like Rickettsia Typhi, an elusive bacterium spread by infected fleas and several others which cannot be tested through commonly available diagnostic technologies continue to pose a huge challenge to healthcare.
The patient had spent a significant amount on various diagnostic attempts, even sending samples overseas to the US, without any conclusive results. After exhausting all other options, the treating physician turned to HaystackAnalytics to identify the infection, stated the company note.
The infexn NGS is a genome sequencing-based diagnostic test capable of detecting pan-bacterial, pan-fungal, and now respiratory viral infections, along with identifying relevant rare and difficult-to-culture organisms, all within 20 hours. Made in India and designed for global application, infexn NGS emerges as the preferred test for detecting infectious diseases. In the myriad of emerging infectious agents, infexn using NGS has now evolved into a versatile diagnostic tool for doctors with several leading hospitals in the country relying on infexn NGS as their go-to infection screening test for their patients, said the company.
This timely diagnosis not only prevented further misdiagnosis but also allowed the medical team to immediately institute the appropriate therapy, leading to the patient's rapid recovery. Several infections like Rickettsia Typhi need targeted therapy to cure the patient and hence their identification plays a major role in the patient outcome.
Dr Mahua Dasgupta Kapoor, director, medical affairs (infectious diseases), HaystackAnalytics, said, Murine typhus is usually spread through bites from infected fleas that live on rats. People can get sick if they come into contact with flea droppings or urine, especially in places where rats are common. Following the successful diagnosis, the patient received the appropriate antibiotics and has shown significant improvement in his condition.”
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