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Akums introduces rabeprazole+levosulpiride SR capsules, addressing needs in GERD treatment

Our Bureau, Mumbai
Monday, June 10, 2024, 15:30 Hrs  [IST]

Akums Drugs & Pharmaceuticals Ltd., one of the country’s largest India-CDMO serving the Indian domestic pharmaceutical industry, has announced the launch of Rabeprazole + Levosulpiride SR Capsules. Approved by the Drug Controller General of India (DCGI), this marks the first time such a formulation has been made available in India, promising relief for patients suffering from gastrointestinal tract (GIT) disorders.
 
GERD, or gastro-oesophageal reflux disease, is a debilitating condition characterised by the reflux of stomach contents into the oesophagus, leading to troublesome symptoms and potential complications. With GERD often dubbed as chronic acid reflux, its prolonged presence not only impacts the quality of life but also poses risks of serious health complications, including stomach and esophageal cancer.
 
Rabeprazole sodium, a potent antisecretory compound, selectively inhibits gastric acid secretion by targeting the H+ and K+ ATPase at the surface of gastric parietal cells. It has demonstrated efficacy in treating gastric and duodenal ulcers, as well as GERD. Complementing rabeprazole, levosulpiride, the levo-enantiomer of sulpiride, exhibits significant central antidopaminergic activity and antiemetic effects. Its peripheral anti-dopaminergic action modulates the motor activity of the upper digestive tract, making it valuable in gastro-enterology.
 
Mr. Sandeep Jain, Joint Managing Director, Akums Drugs & Pharmaceuticals Ltd., added, “The first step to curing any ailment is awareness. It's crucial to raise awareness about GERD to mitigate the risk of developing this condition. The introduction of Rabeprazole + Levosulpiride SR Capsules shows Akums' commitment to providing effective pharmaceutical solutions that cater to medical needs. We are optimistic that this formulation will make a meaningful difference in the lives of patients. I must appreciate the efforts of our R&D team that has helped in bringing this formulation.”
 
Jain added, “The first step to curing any ailment is awareness. It's crucial to raise awareness about GERD to mitigate the risk of developing this condition. The introduction of rabeprazole + levosulpiride SR capsules shows Akums' commitment to effective top-notch pharmaceutical solutions that cater to unmet medical needs. We are optimistic that this novel formulation will make a meaningful difference in the lives of patients. I must appreciate the efforts of our R&D team that has helped in bringing this formulation.”
 
Each hard gelatin capsule contains rabeprazole sodium IP 40 mg (as enteric-coated form) and levosulpiride 75 mg (as uncoated sustained-release form). The recommended dosage is one capsule once daily or as directed by a physician.

 




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