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Daiichi Sankyo to close offices of its subsidiary, Plexxikon to maximize its R&D investment in 3ADCs of Enhertu, Dato-DXd & HER3-DXd

Tokyo, Japan
Thursday, January 13, 2022, 11:00 Hrs  [IST]

Daiichi Sankyo Company, Limited announced that it has decided to close the offices of its research and development subsidiary, Plexxikon Inc., based in South San Francisco, California, to maximize its R&D investment in the three antibody-drug conjugates (3ADCs) of Enhertu, Dato-DXd, and HER3-DXd. Daiichi Sankyo has positioned the “maximize 3ADCs” as one of the strategic pillars of its 5-year Business Plan (FY2021–FY2025).

Plexxikon, with approximately 60 employees, has been engaged in research and development in oncology and neurology since 2001, and as a part of Daiichi Sankyo since 2011, with a portfolio that includes two marketed drugs Zelboraf and Turalio. The existing R&D pipeline at Plexxikon will be transferred to the Daiichi Sankyo Group. Plexxikon will be operational until March 31, 2022 and continue as a legal entity for the time being.

Daiichi Sankyo is dedicated to creating new modalities and innovative medicines by leveraging company’s worldclass science and technology for purpose “to contribute to the enrichment of quality of life around the world.” In addition to the current portfolio of medicines for cancer and cardiovascular disease, Daiichi Sankyo is primarily focused on developing novel therapies for people with cancer as well as other diseases with high unmet medical need.


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