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Scientus's decarboxylated cannabis resins method receives US patent

Friday, December 7, 2018, 10:00 Hrs  [IST]

HydRx Farms Ltd, a biopharmaceutical company conducting research and product development for extracts and formulations related to medical cannabinoids and their derivatives, announced that the United States Patent and Trademark Office (USPTO) has issued US Patent Number 10,143,706, entitled "Decarboxylated Cannabis Resins, uses there of and methods of Making Same."

The patent provides intellectual property protection for Scientus' decarboxylation method for extraction and activation of Active Pharmaceutical Ingredient (API) from natural cannabis plant materials.

"First mover advantage only matters if one can protect it. The granting of this patent is an important step to protect Scientus Pharma's competitive advantage through product innovation," said Har Grover, Chairman and CEO of Scientus. "Our method for extracting and activating cannabis API is unique in the industry and fundamental to our growth strategy. Our method provides intermediary resin that is more than 99 per cent activated for THC and CBD, which maximizes the potency and bioavailability of the API. Our process also yields batches with consistent product profiles, enabling cannabinoid products to reach pharmaceutical-grade standards, rather than just medical-grade."

Scientus has several additional patent applications pending that, if granted, will provide protection for its formulation and processing technologies.

The cannabis plant is highly complex with more than 500 compounds. From a pharmaceutical perspective, cannabis is an amorphous API, which can make it challenging to chemically and biologically profile its active ingredients. There can also be large variations from one harvest to another. Although many growers have developed standardized cultivation methods to reduce variations between harvests, more precision is required to reduce or eliminate this variation and align with the high standards of the pharmaceutical and consumer products industries.

Generally, existing extraction methods do not adequately activate the API, nor do they compensate for large batch-to-batch variation inherent in natural plant materials. Scientus has solved these challenges on both fronts.

Scientus has developed a proprietary method for extraction and activation of API from cannabis, including the profiling phytochemicals and phytocannabinoids. This method provides the chemical and biological quality control appropriate for pharmaceutical grade product lines, resulting in an intermediary resin that can be used in a range of dosing forms.


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